How is Feramax® Pd Therapeutic 150 absorbed?

Polydextrose-iron complex absorption across the cell membrane in the duodenum is mediated by the transporter DMT-1. Once inside the enterocyte, iron can exit into the bloodstream and bind with transferrin or, if the body’s need for iron is met, the iron binds to ferritin inside the enterocyte which will eventually be eliminated. The transferrin-iron complex rapidly delivers iron to bone marrow and red blood cell precursors, where it is taken up by receptor-mediated endocytosis and used to form hemoglobin.

Extra iron is stored primarily in the liver, bone marrow, and to a lesser extent in the spleen.