Frequently Asked Questions by Patients
How is FeraMAX® supplied?

Feramax® Pd Therapeutic 150 is available in a bottle of 100 capsules or carton of 30 capsules.
FeraMAX® Powder is available in an 83 g bottle.

What is FeraMAX® Pd Therapeutic 150?

Feramax® Pd Therapeutic 150 is an oral iron supplement formulated with polydextrose in a stable complex. It is manufactured by a specialized process whereby the iron is coated with polydextrose (starches/sugars). This coating allows the iron to pass through the stomach relatively intact where it is absorbed through the small intestine and is then delivered to the bloodstream.

• It is a dark brown powder which, when dissolved in water forms a very dark brown solution.

• It is virtually tasteless and odorless.

• It is an organic complex and contains no free ions, also described as being non-ionic.

• Due to the polysaccharide coating (matrix) it is electrically neutral.

What conditions/pathologies are at risk for iron deficiency?
  • During pregnancy
  • Menstruating girls and women
  • Pre-term infants and children
  • Iron deficient anemia
  • Hemodialysis
  • Post-gastric bypass or bariatric surgery
  • Hookworm; intestinal parasites
Is FeraMAX® Pd Therapeutic 150 the only polydextrose-iron complex (PDIC) in Canada?

Yes! Feramax® Pd Therapeutic 150 is then only polydextrose-iron complex (PDIC) in Canada.

FeraMAX® was also the original polysaccharide-iron complex (PIC) in Canada. The original PIC was from Schwartz Pharma, which developed, manufactured, and launched the first PIC under the brand name Niferex. Schwartz ultimately transferred its manufacturing rights of this PIC molecule to a third party and Niferex was subsequently discontinued in Canada.

BioSyent Pharma contracted the manufacturing exclusivity of this PIC molecule and then continued to manufacture the product under a new brand, namely FeraMAX®. Consequently, as it is derived directly from the original manufacturing process of PIC, FeraMAX® is the original PIC molecule.

Currently FeraMAX® is the only iron supplement manufactured in a North American FDA approved facility.

Subsequently, there have been several “Branded Generic” PICs launched in Canada trying to leverage the success of this formulation that provides less side effects and convenient once a day dosing.

How is FeraMAX® Pd Therapeutic 150 different from other iron supplements?

Most iron supplements are ferrous (iron) salts. Feramax® Pd Therapeutic 150 is a polydextrose-iron complex. This formulation provides a well tolerated high-dosage of elemental iron. It is also the only iron supplement that is Vegan Certified.

What are the properties of FeraMAX® Pd Therapeutic 150?

Feramax® Pd Therapeutic 150 is positively charged and soluble at pH < 4.0. This solubility at low pH may be associated with improved absorption.
X-ray diffraction analysis shows that polysaccharide-iron complexes have a ferrihydrite (β-FeOOH) structure that closely resembles the structure of ferritin, the natural intracellular protein that binds iron in duodenal cells.

The fact that the polydextrose-iron complex closely resembles endogenous carriers of iron could account for its high bioavailability and reduced side effects.

How is FeraMAX® Pd Therapeutic 150 absorbed?

Polydextrose-iron complex absorption across the cell membrane in the duodenum is mediated by the transporter DMT-1. Once inside the enterocyte, iron can exit into the bloodstream and bind with transferrin or, if the body’s need for iron is met, the iron binds to ferritin inside the enterocyte which will eventually be eliminated. The transferrin-iron complex rapidly delivers iron to bone marrow and red blood cell precursors, where it is taken up by receptor-mediated endocytosis and used to form hemoglobin.

Extra iron is stored primarily in the liver, bone marrow, and to a lesser extent in the spleen.

What is the standard dosage of FeraMAX® Pd Therapeutic 150?

Feramax® Pd Therapeutic 150 delivers 150 mg of elemental iron per capsule – the highest dosage of bioavailable iron in an iron supplement. One capsule per day provides all of the iron necessary for treating iron deficiency and iron deficient anemia.

How is FeraMAX® Powder dosed?

FeraMAX® Powder is dosed at 15mg of elemental iron per 1/4 teaspoon. Please click here to go to the Dosing Information page. Dissolve FeraMAX® Powder in water/juice or mix in soft foods or powdered cereal.

What is the amount of elemental iron per bottle of FeraMAX® Powder?

In an 83 g bottle of FeraMAX® Powder, there is 1800 mg of elemental iron which equals 120 x 15 mg doses of elemental iron.

Is FeraMAX® suitable for Vegan / Vegetarian diets?

Feramax® Pd Therapeutic 150 capsules are Vegan Certified FeraMAX®. The capsules have the active ingredient as our innovative Polydextrose-Iron Complex. It is a hydroxypropylmethylcellulose (HPMC) capsule that is suitable for vegan and vegetarian lifestyles.

This VegeCert logo proves that our product has been audited and inspected by inspectors from Kashruth Council of Canada (COR). These inspectors visit our manufacturing facilities to ensure that FeraMAX® 150 conforms to VegeCert’s high standards.

FeraMAX® Powder does not contain any animal by-product.

Should FeraMAX® Pd Therapeutic 150 be taken with, or without food?

Many oral iron supplements should be taken on an empty stomach; however this increases the likelihood of adverse side effects. Due to its formulation and how it is absorbed, Feramax® Pd Therapeutic 150 can be given with or without food. It is best to take Feramax® Pd Therapeutic 150 at the same time each day.

What is the incidence of side effects experienced by patients with FeraMAX® Pd Therapeutic 150?

Ferrous (iron) salt supplements have a number of unwanted side effects including nausea, vomiting, epigastric pain, and constipation. Because of these adverse effects, many users stop taking their supplements, which can lead to a rapid deterioration of their health. In contrast, most users of polydextrose-iron complex (PIC) supplements report that they experience either very few or no side effects. This increases patient compliance with the supplement dosage and duration prescribed by their physician.

Are there possible interactions between FeraMAX® Pd Therapeutic 150 and other pharmaceuticals?

Because Feramax® Pd Therapeutic 150 is taken only once a day and is rapidly absorbed, it should be possible to safely adjust the dosage schedules and thereby minimize possible interaction in the gastric system. It is generally sufficient if the doses are adjusted so that they are taken a few hours before or after other medication. Use caution when prescribing Feramax® Pd Therapeutic 150 with the following pharmaceuticals:

  • Antacids
  • Tetracyclines (e.g., doxycycline, minocycline, tetracycline)
  • Quinolines (e.g., cipro, floxin, levaquin, tequin)
  • Chloramphenicol
  • Pancreatic enzymes
  • Thyroid hormones
  • Alendronate
  • Cefdinir
  • Etidronate
Are there any specific allergens present in FeraMAX® Pd Therapeutic 150?

Feramax® Pd Therapeutic 150 does not contain lactose, gluten or sulphuric compounds in its formulations. These are the most common ingredients that patients are concerned about. It does contain artificial coloring agents and trace amounts of sodium.

Are there any specific allergens present in FeraMAX® Powder?

FeraMAX® Powder is free of gluten, lactose, sulphuric compounds and alcohol.

Is FeraMAX® Powder safe for babies and children?

Yes, FeraMAX® Powder is safe for babies and children. Click here for further information of the science and safety of FeraMAX®.

Will FeraMAX® Powder stain teeth?

No, FeraMAX® Powder will not stain teeth.

Does FeraMAX® Powder have a metallic taste?

No, FeraMAX® Powder does not have a metallic taste as our polysaccharide-iron complex is tasteless. We have added a pleasant tasting grape/raspberry flavour.

Why is FeraMAX® considered a Natural Health Product?

Health Canada regulations stipulate that all oral iron supplements are now registered as Natural Heath Products and not under the old system of assigning them a Drug Identification Number (DIN). All oral iron products currently on the market have had their DIN’s discontinued and their numbers reassigned to the NHPD (Natural Health Product Directorate).

The approval number for Feramax® Pd Therapeutic 150 is NPN 80075623. The approval number for FeraMAX® Powder is NPN 80033717.

Is FeraMAX® covered under drug insurance plans?

All oral iron products are regulated by Natural Health Product Directorate and thus no longer have a Drug Identification Number (DIN) but rather a Natural Health Product Number (NPN). NPN’s are generally not being covered by drug plans. Some drug plans cover oral iron supplements so we advise to contact your Insurance Company and enquire about coverage.

Where can FeraMAX® be purchased?

FeraMAX® is available across Canada and supplied by all major pharmacy wholesalers/distributors to pharmacies.

How should FeraMAX® be stored?

Store FeraMAX® in a cool dry place (between 15ºC and 30ºC), out of direct sunlight. Keep this and all medicines safely out of the reach of children.

What ingredients are in FeraMAX® Pd Therapeutic 150?

Feramax® Pd Therapeutic 150 capsules can be opened carefully over the sink, and the contents mixed into a glass of water or sprinkled over soft foods.

  • Medicinal ingredient: Polydextrose-iron complex
  • Non-medicinal ingredients: carrageenan, D&C Red #33, D&C Yellow #10, FD&C Blue #1, FD&C Red #40, FD&C Yellow #6, hypromellose, magnesium stearate, microcrystalline cellulose, potassium chloride, and titanium dioxide.
What ingredients are in FeraMAX® Powder?

Dissolve FeraMax Powder in water or mix in soft foods or powdered cereals.

  • Medicinal ingredients: 120 X 15 mg doses of elemental iron
  • Non-medicinal ingredients: Grape and Raspberry flavouring, maltodextrin, sucralose



Please contact BioSyent Pharma Customer Service at 1-888-439-0013
or email for more information.

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I have been prescribing FeraMAX® to my patients. I have no concerns about the gastro-intestinal side effects and the compliance is very good. FeraMAX® is a good product for iron-replacement for patients with iron deficiency.*

Dr. A. Kanjee MD.CCFP, Richmond Hill, ON